Labzee Hybridizers are advanced instruments designed for precise temperature-controlled hybridization of nucleic acid probes to target sequences. They ensure uniform heating and agitation during in situ hybridization (ISH) and fluorescence in situ hybridization (FISH) procedures. These systems offer programmable protocols, uniform temperature distribution, and humidity control to maintain optimal conditions for consistent results. Their intuitive controls, secure chamber sealing, and compatibility with multiple slide formats make them a dependable choice for molecular diagnostics. Our Hybridizers are ideal for use in genetics labs, cytogenetics, oncology diagnostics, and molecular research facilities.
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Frequently Asked Questions
1: When is a Hybridizer used in the lab?
It is used for FISH and ISH protocols to bind DNA or RNA probes to specific sequences. The device maintains stable temperature and humidity for accurate results. It is essential for gene expression and chromosomal studies.
2: Can differently slide formats be used with the Hybridizer?
Yes, most models accommodate standard microscope slides and various slide racks. Custom holders may be available for high-throughput applications. Ensure compatibility with your specific slide setup.
3: Can temperature and humidity be controlled independently?
Yes, Hybridizers feature programmable temperature and, in some models, humidity settings. Independent control ensures precise hybridization conditions. These settings can be saved for repeated use.
4: When should calibration and validation be performed?
Calibration is recommended every 6–12 months depending on usage frequency. Routine validation ensures consistency in diagnostic and research results. Check manufacturer guidelines for your specific model.
5: Can it be used for both DNA and RNA hybridization?
Yes, Hybridizers are suitable for both DNA and RNA probe binding. Temperature and timing can be adjusted to match the protocol. Always follow the assay’s recommended parameters.